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2 540 116

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(51)

IPC

C07D233/58(2006-01-01)

C07D233/56(2006-01-01)

A61K31/4172(2006-01-01)

A61K31/4174(2006-01-01)

A61P23/00(2006-01-01)

(21) (22)

Application

2010144523/04, 2009-03-31

(24)

Start date

2009-03-31

(22)

Actual filing date

2009-03-31

(45)

Published

2015-02-10

(72)

Inventor

Rejnz Duglas E.Forman Stjuart A.Miller Kejt V.Khusejn Sajed ShaukatKotten Dzhozef F.

(73)

Holder

Dze Dzheneral Khospital Korporejshn

ETOMIDATE ANALOGUES WITH IMPROVED PHARMACOKINETIC AND PHARMACODYNAMIC PROPERTIES Russian patent published in 2015 - IPC C07D233/58 C07D233/56 A61K31/4172 A61K31/4174 A61P23/00

Abstract RU 2540116 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to organic chemistry, namely to benzimidazole derivatives of general formula (I) and to their pharmaceutically acceptable salts, mixed stereoisomers and enantiomers, wherein R₁ is L₁C(O)OL₂C(O)OT; R₂ is unsubstituted C₁-C₁₀alkyl; L₁ is a bond; L₂ is unsubstituted C₂-C₁₀alkylene; T is C₁-C₁₀alkyl. Also, the invention refers to a pharmaceutical composition of the compound of formula (I) and a method of anaesthetising on the basis of using the compound of formula (I).

EFFECT: there are prepared new imidazole derivatives effective as an anaesthetising agent.

15 cl, 9 dwg, 15 ex

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RU 2 540 116 C2

Authors

Rejnz Duglas E.

Forman Stjuart A.

Miller Kejt V.

Khusejn Sajed Shaukat

Kotten Dzhozef F.

Dates

2015-02-10—Published

2009-03-31—Filed