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2 806 363

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IPC

A61K31/167(2006-01-01)

A61K31/381(2006-01-01)

A61K9/14(2006-01-01)

A61K47/04(2006-01-01)

A61K47/36(2006-01-01)

A61P23/00(2006-01-01)

(21) (22)

Application

2023110670, 2023-04-25

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Start date

2023-04-25

(22)

Actual filing date

2023-04-25

(45)

Published

2023-10-31

(72)

Inventor

Lomachkina Marina SergeevnaKulikov Oleg AleksandrovichAgeev Valentin PavlovichShliapkina Vasilisa IgorevnaZharkov Mikhail NikolaevichIakobson Denis EduardovichPiataev Nikolai Anatolevich

(73)

Holder

Lomachkina Marina Sergeevna

NANOSUSPENSION BASED ON ALGINATE-CHITOSAN POLYELECTROLYTE COMPLEX WITH ARTICAINE HYDROCHLORIDE FOR LOCAL ANESTHESIA Russian patent published in 2023 - IPC A61K31/167 A61K31/381 A61K9/14 A61K47/04 A61K47/36 A61P23/00

Abstract RU 2806363 C1

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to a nanosuspension based on an alginate-chitosan polyelectrolyte complex with articaine hydrochloride for local anesthesia, containing the following ratio of components, wt.%: sodium alginate 0.015–0.018; calcium chloride 0.025–0.03; chitosan 0.008–0.01; articaine hydrochloride 0.95–1.0; and the rest is deionized water.

EFFECT: invention provides an increase in the local anesthetic effect, a decrease in toxicity and pain effect directly from the administration, and the safety of future use.

1 cl, 6 dwg, 2 tbl, 1 ex

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RU 2 806 363 C1

Authors

Lomachkina Marina Sergeevna

Kulikov Oleg Aleksandrovich

Ageev Valentin Pavlovich

Shliapkina Vasilisa Igorevna

Zharkov Mikhail Nikolaevich

Iakobson Denis Eduardovich

Piataev Nikolai Anatolevich

Dates

2023-10-31—Published

2023-04-25—Filed