METHOD OF DETERMINING BIOLOGICAL ACTIVITY OF EMBRYONATED EGGS OF TRICHURIS Russian patent published in 2015 - IPC C12Q1/68 G01N33/533 A01K67/33 

Abstract RU 2540145 C2

FIELD: medicine.

SUBSTANCE: invention deals with method of determining biological activity of embryonated eggs of Trichuris. Characterised method includes realisation of at least 3 analyses, selected from: evaluation and/or confirmation of stage of embryonated development of eggs by means of method of quantitative PCR with application of suitable marker sequences for determination of quantity of genome DNA copies, evaluation of metabolic activity of embryonated eggs by means of biochemical and/or molecular-chemical methods, evaluation of inducibility of gene expression in embryonated eggs, evaluation of mobility of Trichurs larvae by means of microscope for long periods of observation after preliminary incubation at higher temperatures and/or evaluation of coefficient of hatchability of Trichurs larvae in organism of laboratory animal.

EFFECT: claimed invention can be used in obtaining safe pharmaceutical products, therapeutically efficient in application in humans.

15 cl, 10 dwg, 11 tbl, 6 ex

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RU 2 540 145 C2

Authors

Bernkhard Teves

Rudol'F Vil'Khel'M

Dates

2015-02-10Published

2009-05-20Filed