COMPOSITIONS AND METHODS FOR IMPROVING DRUG THERAPY WITH METAL ION DEPENDANT AGENTS Russian patent published in 2015 - IPC A61K33/30 A61K38/46 A61K39/08 A61P25/00 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to a preparatory kit presented to a patient before administering a therapeutic botulinum toxin. The declared kit contains an additive in the form of capsules or tablets, which comprise zinc ions in the organic or inorganic form in a sufficient dose of 10mg to 400mg of elementary zinc a day, and a phytase additive in an amount of 0.8-10,000 units sufficient to be administered together with the ion zinc additive for the period of zinc ion load. The preparatory kit also comprises a package insert providing the patient with recommendations to administer the zinc ion additives and to reduce the phytate dose.

EFFECT: zinc dose provides activating the therapeutic botulinum toxin for the period of zinc ion load before initiating the therapy with the therapeutic botulinum toxin.

4 cl, 1 tbl, 3 dwg, 2 ex