TREATMENT OF FACIAL WRINKLES WITH HIGH DOSE AND SMALL AMOUNT OF BOTULINUM TOXIN Russian patent published in 2025 - IPC A61K38/48 A61P17/00 

FIELD: medicine.

SUBSTANCE: group of inventions refers to medicine, namely to cosmetology, and can be used for treating facial wrinkles. Use and method according to the invention relate to the introduction of botulinum toxin by injection into the face of a subject in a total dose of 80 to 120 units and a total volume of 0.15 ml to 0.30 ml, where brow wrinkles are moderate or pronounced brow wrinkles based on the assessments of the researcher using the facial wrinkle scale (FWS) with maximum frown. Botulinum toxin, which is a neurotoxic component of serotype A botulinum toxin, is injected into 5 points of intramuscular injection.

EFFECT: use of inventions enables to achieve a stable positive effect with good tolerance, enables to avoid side effects - signs of a frozen face - due to a combination of high doses of botulinum toxin and low volumes of injections.

8 cl, 13 dwg, 2 ex