METHOD FOR SIMULATION AND PHARMACEUTICAL CORRECTION OF ACUTE PULMONARY INJURY EXPERIMENTALLY Russian patent published in 2015 - IPC G09B23/28 A61K31/718 A61K33/14 A61P11/00 

Abstract RU 2541831 C2

FIELD: medicine.

SUBSTANCE: pulmonary injury is simulated by the intratracheal administration of acetone 0.03ml into rats. One hours later, a combined solution containing 7.2% sodium chloride and 6% hydroxyethyl starch, in an amount of 4 ml/kg is administered intravenously once.

EFFECT: reducing animal mortality by reducing hypoxemia and an area of the infiltrative pulmonary injury, preventing an alveolar pulmonary oedema and a degree of haemorrhagic impregnation.

2 dwg, 2 tbl

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Authors

Kulikov Oleg Aleksandrovich

Inchina Vera Ivanovna

Semenov Aleksandr Vladimirovich

Semenova Elena Vasil'Evna

Dates

2015-02-20Published

2013-06-25Filed