PEPTIDES-DERIVATIVES IL-4 FOR MODULATION OF CHRONIC INFLAMMATORY RESPONSE AND TREATMENT OF AUTOIMMUNE DISEASES Russian patent published in 2015 - IPC C07K14/435 

Abstract RU 2542375 C2

FIELD: pharmacology.

SUBSTANCE: small peptides are described, which are derivatives of cytokine, interleukin-4 (IL-4), capable of binding receptors of IL-4 and inhibiting activation of macrophages and thus preventing start of the inflammatory response. Besides, the invention relates to application of the specified peptides for manufacturing of a medicinal agent for treatment of various pathological conditions, where a significant role is played by IL-4.

EFFECT: invention expands arsenal of agents for treatment of various pathological conditions, in which a significant role is played by IL-4.

18 cl, 17 dwg, 4 ex

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Authors

Bokk Ehlisabet

Berezin Vladimir

Dates

2015-02-20Published

2009-11-17Filed