FIELD: pharmacology.
SUBSTANCE: small peptides are described, which are derivatives of cytokine, interleukin-4 (IL-4), capable of binding receptors of IL-4 and inhibiting activation of macrophages and thus preventing start of the inflammatory response. Besides, the invention relates to application of the specified peptides for manufacturing of a medicinal agent for treatment of various pathological conditions, where a significant role is played by IL-4.
EFFECT: invention expands arsenal of agents for treatment of various pathological conditions, in which a significant role is played by IL-4.
18 cl, 17 dwg, 4 ex
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Authors
Dates
2015-02-20—Published
2009-11-17—Filed