FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology and represents isolated polyspecific antibodies against a unique epitope in chemokine eotaxine 2, whereby antibodies bind to additional CCR3-binding chemokines. Invention also relates to the use of said antibodies for mitigating migration of different cells and for treating fibrotic diseases, autoimmune inflammatory disorders, monocyte-related disorders, or allergic atopic disorders.
EFFECT: invention provides higher clinical effectiveness in the above diseases.
19 cl, 32 dwg
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Authors
Dates
2019-11-06—Published
2015-03-04—Filed