ANTIBODIES AGAINST EOTAXIN 2, WHICH RECOGNIZE ADDITIONAL CCR3-BINDING CHEMOKINES Russian patent published in 2019 - IPC C07K16/24 C12N15/63 

Abstract RU 2705255 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology and represents isolated polyspecific antibodies against a unique epitope in chemokine eotaxine 2, whereby antibodies bind to additional CCR3-binding chemokines. Invention also relates to the use of said antibodies for mitigating migration of different cells and for treating fibrotic diseases, autoimmune inflammatory disorders, monocyte-related disorders, or allergic atopic disorders.

EFFECT: invention provides higher clinical effectiveness in the above diseases.

19 cl, 32 dwg

Similar patents RU2705255C2

Title Year Author Number
ANTIKINE ANTIBODIES BINDING TO SEVERAL CC-CHEMOKINES 2010
  • Ehllison Dehn
  • Rehport Kehrol
RU2574786C2
ANTIBODIES RAISED TO HUMAN MCP-1 2001
  • Khishtand Peter
  • Khofshtetter Khans
  • Pejn Trevor Glin
  • Urfer Roman
  • Di-Padova Franko Eh.
RU2314316C2
ANTIBODY AND CHEMOKINE CONSTRUCTS AND USES THEREOF IN IMMUNOLOGICAL DISORDERS 2001
  • Mak Mattias
  • Shloendorff Detlef
  • Shpring Mikhael'
RU2252786C2
ANTAGONISTS AND METHOD OF USING SAID ANTAGONISTS 2005
  • Brjuis Nil D.
  • Vulven Bendzhamin P.
  • Kholms Stiv
  • Tomlinson Ajan M.
  • Li Dzhennifer
  • Ehnever Karolin
  • Basran Amrik
  • Dzhouns Kejt
  • Vildt Ruud De
  • Blejn Stanislas Charlz
RU2401842C2
ANTIBODY AGAINST CCR5 2003
  • Olson Vill'Jam S.
  • Maddon Pol Dzh.
  • Tsurusita Naoja
  • Khinton Pol R.
  • Vaskes Maksimillano
RU2322454C2
ANTIBODIES TO INTERLEUKIN-6 AND USES THEREOF 2013
  • Lin Willie
  • Lee Tong-Youn
  • Wu Han-Chung
  • Tsao Tanny Chen
RU2656162C2
NEUTRALIZING MONOCLONAL HUMAN ANTI-INTERLEUKIN-33 ANTIBODIES 2014
  • Fudzino Yasukhiro
  • Esikava Tsutomu
  • Oti Khirosi
RU2709722C1
IL-17A LINKING AGENT AND METHODS FOR USE THEREOF 2014
  • Chzhan Lyanshan
  • Lyu Tszyatszyan
  • Tsao Gotsin
  • Sun Pyaoyan
RU2682046C1
NEW MODULATORS AND METHODS OF THEIR APPLICATION 2012
  • Foord Orit
  • Dylla Scott J.
  • Stull Robert A.
  • Bankovich Alex
  • Lazetic Alexandra Leida Liana
  • Bernstein Jeffrey
RU2627176C2
ANTI-NOTCH1 ANTIBODIES 2011
  • Geles Kenneth G.
  • Zhou Bin-Bing Stephen
  • Tchistiakova Lioudmila Gennadievna
  • Gao Yijie
  • Bard Joel
RU2622083C2

RU 2 705 255 C2

Authors

Mor Adi

Dates

2019-11-06Published

2015-03-04Filed