FIELD: chemistry.
SUBSTANCE: method includes reacting anilines of general formula R-C6H4NH2 (where R=H, o-, m-, n-CH3, o-C2H5, o-, m-, n-Cl, n-F) and α,ω-diols (1,4-butanediol, 1,5-pentanediol) in the presence of a catalyst FeCl3·6H2O in the medium of tetrachloromethane at 180°C for 4-8 hours with molar ratio [FeCl3·6H2O]:[RC6H4NH2]:[diol]:[CCl4]=0.2-0.5:100:100-400:20-100. At 180°C and reaction duration of 6 hours, output of N-arylpyrrolidines reaches 45-88%, and output of N-arylpiperidines reaches 33-85%. Synthesis is carried out in an argon atmosphere.
EFFECT: method reduces reaction time and enables to use more affordable catalyst.
1 tbl, 33 ex
| Title | Year | Author | Number |
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