METHOD OF PRODUCING CHLORINE-SUBSTITUTED 4,4'-DIAMINOBENZANILIDES Russian patent published in 2015 - IPC C07C233/80 C07C231/02 

FIELD: chemistry.

SUBSTANCE: method is carried out by acylation of a corresponding chloronitroaniline with 4-nitrobenzoyl chloride in an organic solvent while heating under pressure of a current of an inert gas, reducing the formed chlorine-substituted 4,4'-dinitrobenzanilide in an amide solvent selected from dimethyl formamide, dimethyl acetamide, N-methyl pyrrolidone, with separation of the end product in the form of a salt of a mineral acid in the presence of a lower aliphatic alcohol or acetone, followed by neutralisation of the salt with a base. Acetylation is carried out under pressure of a current of an inert gas of up to 0.3 MPa. The chlorine-substituted 4,4'-dinitrobenzanilide is reduced with hydrogen in the medium of an amide solvent in the presence of a catalyst based on platinum or palladium or other platinum group metals on a support or palladium which is modified with nickel and iron on a support, or a skeleton nickel or nickel-chromium catalyst or with iron in the presence of an electrolyte.

EFFECT: improved process of producing end products, which comprises cutting the duration of the acylation step, improving the reliability of the hydrogen chloride absorption system, improving the efficiency of the reducing step, reducing power consumption when recovering the amide solvent and improving the quality of the end products.

3 cl, 6 tbl, 19 ex