METHOD OF EVALUATING TOLERANCE TO PHYSICAL LOADING BY MEASUREMENT OF AUTOFLUORESCENT PROPERTIES OF SKIN Russian patent published in 2015 - IPC A61B5/00 A61B5/1455 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to functional diagnostics, and can be applied for the evaluation of tolerance to physical loading. Skin is illuminated by exciting radiation. Signals, generated by the secondary skin irradiation, are measured by a spectrometer in two spectral areas. The first spectral area is selected from the field of excitation, the second - in the area of fluorescent NADH emission. Evaluation of the autofluorescent AF parameter is carried out in accordance with formula: AF=F(λ_m)/R(λ_x)^0.85, where R(λ_x) is a signal, obtained from the first spectral area, F(λ_m) is a signal, obtained from the second spectral area. Measurement of the signals is carried out in symmetric zones of the right and left parts of the body in an initial condition of the human organism. Then, the human organism is influenced by a loading test, and the measurement of signals is performed in the same areas of the skin. The index of the functional status IFS is calculated by formula: IFS=AF_o/AF_p, where AF_o is the parameter of autofluorescence before the influence with the loading test, AF_p is the parameter of autofluorescence after the influence with the loading test. The value of AF_p, maximally different from AF_o is used_. Tolerance to physical load is evaluated by the obtained value of IFS.

EFFECT: method makes it possible to increase the reliability of estimation of tolerance to physical loading due to the differential principle of measurement, in which only changes of the skin autofluorescence, associated with NADH changes, are traced, as well as to reduce the evaluation time.

4 dwg, 1 tbl