HARDWARE-SOFTWARE COMPLEX FOR ESTIMATING CONDITION OF RESPIRATION REGULATING SYSTEM AND METHOD OF APPLICATION THEREOF Russian patent published in 2015 - IPC A61B5/08 

FIELD: medicine.

SUBSTANCE: elaborated hardware-software complex is intended for application in conditions of a polyclinic, in limited closed volumes, with a person staying in which can be connected with the change of the respiratory centre sensitivity to breathing gases (O₂ and CO₂) in a changed gas medium, as well as in specialised research institutions for carrying out experiments aimed at the study of the human cardiorespiratory system. The elaborated complex consists of three units: a unit of gas distribution (A1), a unit of gas supply (A2), a unit of collection and processing data and system control (A3). Unit A1 represents a closable and openable breathing circuit. The unit includes the following main elements, connected to each other by means of tubes: a metal reservoir with a bag, a ventilator, a chemical absorber of carbon dioxide (CA), a regulator of flow through CA, a system of valves and three-way taps, hoses, a valve box, as well as a device, made with a possibility of realisation of biological feedback (BFB) by the patient's noting their state and transmission of data about the state into a terminal device of unit A3. The unit of gas supply is made with a possibility of regulated supply of gases into unit A1 by means of an electrically controlled choke, with atmospheric air or atmospheric air with an increased or reduced oxygen content being used as the supplied gases. The unit of collection and processing of data and system control includes a terminal device with software, realising control over movement of the gases and their parameters in unit A1. The said control is possible in a manual, automatic mode; as well as with an account of signals, obtained from BFB device; sensors of concentrations of gases, sensors of flows, sensors of measurement of physiological parameters, information from which is transmitted into the terminal device by means of a converter. The method of estimating the condition of the respiration regulating system by means of the elaborated hardware-software complex includes carrying out a number of stages. First, a preparatory stage is realised at which the dosed supply of gases from the unit of gas supply (A2) into the unit of gas distribution (A1) is performed. Continuous mixing of the gases in the respiratory circuit is realised during the time of supply of the gases into unit A1 in course of entire rebreathing by operation of an air pump. After that, a stage of estimating the condition of the respiration regulating system is performed, for which purpose the tested person is connected to a respirator, connected to the valve box via a filter, and performs breathing through the mouth with the closed nasal way, with inhalation being made through an inhalation hose and exhalation - through an exhalation hose. At the beginning of the stage of estimating the condition of the respiration regulating system HSC is set in a free respiration mode, in which the respiratory circuit is closed, and the tested person performs breathing with atmospheric air through the inhalation and exhalation hoses, the system of three-way taps, with the determination of a value of partial oxygen, carbon dioxide in alveolar air and ventilation of the tested person's lungs. After that, a manoeuvre of arbitrary hyperventilation is performed in the free respiration mode until a specified safe gas composition of exhaled air is achieved. After that, by switching the three-way taps the tested person passes into the mode of rebreathing, before which the tested person performs deep exhalation into atmosphere, then realises inhalation-exhalation from the circuit. The tested person breathes from the box space outside the bag, atmospheric air enters and leaves the bag simultaneously through the sensor of the air flow, with measuring in this way parameters of lung ventilation. Finally, transfer into the free respiration mode is performed by switching the three-way taps. The said results are achieved due to the possibility of applying only own metabolic carbon dioxide for performing a hypercapnic impact; application of the principle of complex control by means of feedback; application of an oxygen generator for filling the system with a hyperoxic mixture and dosed supply of oxygen into the system, applied in the test of respiration with the hyperoxic gas mixture and with the support of constant oxygen concentration (isooxic gas mixture) in the system; automation of measurements.

EFFECT: provision of safe, objective and comprehensive estimation of operation of the person's respiration regulating system.

31 cl, 4 dwg