METHOD FOR DETERMINATION OF READINESS OF WEANING FROM EQUIPMENT OF ARTIFICIAL VENTILATION OF LIGHT PATIENTS WITH CEREBRAL INJURIES Russian patent published in 2019 - IPC A61B5/08 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to resuscitation, and can be used for determination of readiness of weaning from artificial pulmonary ventilation (APV) of patients with cerebral injuries. Peripheral chemoreflex sensitivity is quantitatively assessed by evaluating external respiration values: minute volume of respiration (MVR) in l/min, respiratory rate (RR) in min^-1, respiratory volume (RV) in l/min initially and after carrying out functional loading test. Sample is carried out in the form of independent breathing with oxygen-air mixture 1:1 using a closed breathing circuit of the rebreather, in which the oxygen content decreases as it is absorbed by the patient's body, until the first episode of desaturation of hemoglobin with oxygen spO₂ in range of 90–80 %. Peripheral chemoreceptor sensitivity index is calculated by formula PCSI=(RRi:RRe)×(RVi:RVe)×(MVRi:MVRe)×RVe×MVRe, where PCSI is the peripheral chemoreceptor sensitivity index; RRi is the respiratory rate initially before the functional loading test; RRe is respiratory rate when saturation of hemoglobin with oxygen – spO₂, in range of 90–80 %; RVi – respiratory volume initially before carrying out functional loading test (l/min); RVe – respiratory volume with oxygen saturation of hemoglobin – spO₂, in range of 90–80 % (l/min); MVRi is a minute volume of respiration recorded initially before the functional loading test (l/min); MVRe is a minute volume of breathing when saturation of hemoglobin with oxygen – spO₂ in range of 90–80 % (l/min). If values of PCSI are more than 31 make a conclusion on the possibility of successful implementation of programs for weaning from artificial pulmonary ventilation.

EFFECT: method provides an individual assessment of the possibility of a patient on APV to breathe independently by determining the sensitivity of the chemoreflex on the background of the functional load.

1 cl, 7 ex