FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to a method for producing 2-methylene-1,3-dinitroxypropane. The method involves a reaction of silver nitrate and tris(chloromethyl)acetic acid in the acetonitrile medium. The reaction is performed at heating to 60-70°C.
EFFECT: method enables producing the good yield product from the accessible compound in the comfortable medium as well as reducing the number of stages.
5 dwg, 5 tbl
Title | Year | Author | Number |
---|---|---|---|
USE OF 2-METHYLENE-1,3-DINITROXYPROPANE AS ANTI-ISCHEMIC AGENT | 2015 |
|
RU2580929C1 |
ANTIISCHEMICALLY-ACTIVE AGENT | 1988 |
|
RU2007985C1 |
PEPTIDE COMPOUND RECOVERING FUNCTION OF MYOCARDIUM | 2004 |
|
RU2255756C1 |
METHOD OF PROPHYLAXIS AND TREATMENT OF PATIENT WITH MYOCARDIUM ISCHEMIA IN CORONARY-INVASIVE OPERATIONS | 1999 |
|
RU2146933C1 |
"INFUSOL" CARDIOPLEGIC SOLUTION | 2002 |
|
RU2226093C1 |
METHOD OF DETERMINING REPERFUSED INJURY OF MYOCARDIUM AFTER ISCHEMIA | 0 |
|
SU1570707A1 |
METHOD TO PREVENT AFTEREFFECTS AND COMPLICATIONS OF INDUCED CARDIAC ISCHEMIA | 1993 |
|
RU2083219C1 |
2-MERCAPTOBENZIMIDAZOLE DERIVATIVES SHOWING ANTI-ISCHEMIC, ANTI-ARRHYTHMIC AND ANTIFIBRILLATORY ACTIVITY | 1995 |
|
RU2136667C1 |
METHOD FOR PRESERVING MYOCARDIUM ACCOMPANYING TRANSPLANTATION | 2013 |
|
RU2535036C1 |
5-BROMONICOTINIC ACID DERIVATIVES WITH ANTI-ARRHYTHMIC ACTIVITY | 2015 |
|
RU2617428C2 |
Authors
Dates
2015-06-10—Published
2013-09-05—Filed