"INFUSOL" CARDIOPLEGIC SOLUTION Russian patent published in 2004 - IPC

Abstract RU 2226093 C1

FIELD: medicine. SUBSTANCE: the present innovation deals with elaborating the formulas of solutions applied in conducting the so-called "open heart" operations. Polyionic buffer cardioplegic solution has got osmolarity of 350±5 mOsm, contains sodium chloride, potassium chloride, calcium chloride, magnesium chloride, potassium asparaginate, magnesium asparaginate, mannitol, trisamine and water for injections at the following ratio of components, weight%: sodium chloride 0.63-0.77, potassium chloride 0.027-0.033, magnesium hexachloride 0.18-0.22, calcium hexachloride 0.009-0.011, potassium semi-water asparaginate 0.20-0.24, magnesium tetraasparaginate 0.17-0.19, mannitol 0.32-0.38, trisamine 0.05-0.07, water for injections the rest, moreover, pH of solution corresponds to 7,6±0,1 at 22 C. Composition of "Infusol" provides sufficient improvement in restoring the function and metabolism of heart at reperfusion after stoppage of artificial circulation. EFFECT: higher efficiency. 1 dwg, 7 tbl

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RU 2 226 093 C1

Authors

Pisarenko O.I.

Studneva I.M.

Shul'Zhenko V.S.

Dates

2004-03-27Published

2002-11-05Filed