DETERMINATION OF CELL SENSITIVITY TO TREATMENT WITH B-Raf INHIBITOR BY DETECTION OF K-ras MUTATION AND LEVELS OF RTK EXPRESSION Russian patent published in 2015 - IPC G01N33/48 

Abstract RU 2553379 C2

FIELD: medicine.

SUBSTANCE: invention relates to field of medicine. Claimed is method, including determination of presence or absence of K-rasG12D mutation. Presence of K-rasG12D mutation points to the fact that patient will not respond to treatment with B-Raf inhibitor.

EFFECT: invention provides effective method of identifying patient who does not respond to treatment with B-Raf inhibitor.

6 cl, 34 dwg, 12 tbl, 3 ex

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RU 2 553 379 C2

Authors

Khatzivassiliu Dzhordzhija

Malek Shiva

Dates

2015-06-10Published

2010-08-24Filed