FIELD: medicine, pharmaceutics.
SUBSTANCE: group of inventions refers to methods of treating type 2 diabetes, insulin resistance, insulin hyposecretion, obesity, hyperglycaemia and hyperinsulinemia, involving administering an effective amount of an anti-IL-1β antibody or its fragment into an individual, as well as to using the anti-IL-1β antibody or its fragment in preparing a composition applicable for treating the above diseases or conditions.
EFFECT: group of inventions is effective in treating type 2 diabetes mellitus, insulin resistance, insulin hyposecretion, obesity, hyperglycaemia and hyperinsulinemia.
67 cl, 13 dwg, 5 tbl, 14 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF TREATMENT OF PATHOLOGICAL DEVIATIONS AT DIABETES MELLITUS OF TYPE-2 | 1992 |
|
RU2104698C1 |
| FUSED DRUG CONSTRUCTS AND CONJUGATES | 2005 |
|
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| APPLICATION OF NKG2D INHIBITORS FOR TREATING CARDIOVASCULAR AND METABOLIC DISEASES SUCH AS TYPE 2 DIABETES | 2010 |
|
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| TREATING DISEASES RELATED TO INSULIN RESISTANCE | 2010 |
|
RU2537142C2 |
| MATERIALS AND METHODS FOR METABOLISM MODULATION | 2005 |
|
RU2387445C2 |
| IL-1beta-BINDING ANTIBODIES AND FRAGMENTS THEREOF | 2006 |
|
RU2518295C2 |
| COMPOSITIONS, APPLICATIONS AND METHODS OF TREATING METABOLIC DISORDERS AND DISEASES | 2012 |
|
RU2697762C2 |
| WAYS AND COMPOSITIONS FOR ADIPOSITY TREATMENT, INSULIN-DEPENDENT DISEASES AND HYPERCHOLESTERINEMIA | 2005 |
|
RU2359689C2 |
| METHODS OF TREATING DIABETES AND/OR PROMOTING SURVIVAL OF PANCREATIC ISLETS AFTER TRANSPLANTATION | 2013 |
|
RU2667960C2 |
| METHODS OF REGULATION OF GASTROENTERIC TRACT MOTOR SYSTEM | 1994 |
|
RU2177331C2 |
