FIELD: medicine, endocrinology. SUBSTANCE: invention relates to long-term modification and regulation of lipid and carbohydrate metabolism at insulin-nondependent diabetes mellitus, or type-2. Method involves oral, sublingual or parenteral administration of bromocriptin (dopamine agonist) to human or animals. Bromocriptin is administrated depending on normal circadian rhythm of insulin-resistant and insulin-sensitive persons or animals. Resistance to insulin, hyperinsulinemia and hyperglycaemia or both can be regulated in human on long-term base using this treatment since short-term daily administration of preparation corrects hormonal "schedule" in brain nervous centers that results to long-term effect. EFFECT: enhanced effectiveness of method. 20 cl, 4 tbl
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Authors
Dates
1998-02-20—Published
1992-12-22—Filed