FIELD: medicine.
SUBSTANCE: invention relates to method of diagnosing rheumatoid arthritis, method of determining therapeutic agent for treatment of rheumatoid arthritis and set for realisation of methods. Methods are characterised by the fact that include stage of measuring amount of talin in plasma or serum of animal subject. Said measurement is carried out, for instance, by immunologic method with application of antibody, binding with talin. If amount of talin is higher than its average value in control subject without rheumatoid arthritis, rheumatoid arthritis is diagnosed in subject. In case of reduction of talin amount after introduction of therapeutic agent in comparison with amount of talin before introduction, therapeutic effect is stated. Set in accordance with claimed invention contains solid-phase carrier, to which antibody, binding with talin, is attached.
EFFECT: increased efficiency of diagnostics.
9 cl, 4 tbl, 4 ex, 3 dwg
Title | Year | Author | Number |
---|---|---|---|
METHOD FOR PREDICTING EFFECTIVENESS OF TREATMENT OF RHEUMATOID ARTHRITIS WITH DRUG OLOKIZUMAB USING EPIGENETIC MARKERS | 2020 |
|
RU2749248C1 |
COMPOSITIONS FOR RHEUMATOID ARTHRITIS TREATMENT AND METHODS OF THEIR APPLICATION | 2012 |
|
RU2664697C2 |
METHOD FOR PREDICTING THE EFFECTIVENESS OF METHOTREXATE THERAPY IN PATIENTS WITH RHEUMATOID ARTHRITIS | 2020 |
|
RU2753793C1 |
MEDICATION FOR TREATMENT OF RHEUMATOID ARTHRITIS | 2010 |
|
RU2524152C2 |
METHODS OF TREATING RHEUMATOID ARTHRITIS USING IL-17 ANTAGONISTS | 2011 |
|
RU2582937C2 |
METHOD OF TREATING PATIENTS WITH RHEUMATOID ARTHRITIS | 2013 |
|
RU2554232C1 |
METHOD OF TREATING PATIENTS WITH RHEUMATOID ARTHRITIS | 2013 |
|
RU2573631C2 |
GM-CSF-NEUTRALIZING ANTIBODIES FOR USE IN TREATING RHEUMATOID ARTHRITIS OR AS ANALGESICS | 2014 |
|
RU2714919C2 |
METHOD OF TREATING PATIENTS WITH RHEUMATOID ARTHRITIS | 2014 |
|
RU2573998C1 |
METHOD OF TREATING RHEUMATOID ARTHRITIS | 2018 |
|
RU2709141C1 |
Authors
Dates
2015-06-27—Published
2011-06-14—Filed