METHOD OF TREATING ACUTE AND CHRONIC WOUNDS Russian patent published in 2015 - IPC A61M27/00 A61M1/00 A61F13/00 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to purulent surgery, and can be used to treat acute and chronic septic wounds. That is ensured by pre-measuring patient's capillary wall resistance on the involved body area, which is covered with a vacuum dressing, underneath which a low pressure within the range of 50-200 torr is generated for a period of time being no more than 20 times greater than the resistance time. Once this period of time expires, the wound is drained and bathed at the above low pressure by administering an antiseptic, which is presented by an anolyte with hydrogen concentration pH_an falling within the range of 2≤(pH)_an≤4, and the oxidation-reduction potential (Eh)_an ranging from [1,000≤(Eh)_an≤1,200] mV. The drainage and bathing procedures last for 5-10 minutes. That is followed by 3-5-minute pressure reset, and the anolyte supply is shut off; the anolyte with the wound discharge is evacuated until the pressure underneath the vacuum dressing re-drops to 50-200 torr. Thereafter, the anolyte is re-supplied to the wound through a drain tube. The cycles are alternated for 5-8 times. The vacuum dressing is removed from the septic wound, and the necrotic tissue areas are covered with pepsin powder and dressed or drained through anolyte gauze drain sponges. A 4-6-hour break is followed by replacing the anolyte dressing with pepsin by the vacuum dressing, and the similar alternating process mentioned above is repeated. The procedure is performed 2 or 3 times a day for 3 or 5 days within the therapeutic course. As the wound heals, and the local oedema and bacterial content decrease, the above therapeutic cycle is to be repeated. The flushing drainage and bathing therapy involves replacing the anolyte by catholyte, the hydrogen concentration pH of which lies in the range of 8≤(pH)_an≤13, whereas the oxidation-reduction potential (Eh)_cat varies within [-820≤(Eh)_cat≤-300] mV. As the catholyte flows to the wound, infrasonic vibrations of the power of 10^-2 to 1 W/cm² continuously and periodically varying within the range of 10 to 30 Hz and back are excited. The drainage and bathing procedure with the periodic ultrasound in the above frequency range lasts for 15-20 minutes. The ultrasound is switched off, the catholyte supply is shut off from the wound until the pressure underneath the vacuum dressing re-drops to 50-200 torr. The catholyte flows to the wound again, and infrasonic vibrations of the power of 10^-2 to 1 W/cm² continuously and periodically varying within the range of 10 to 30 Hz and back are excited. The cycles are alternated for 5-8 times. Once the catholyte evacuation from the wound is terminated, the last cycle of the alternating process involves removing the dressing from the healing wound, however tissues impregnated with the catholyte are left in the wound. The above procedure is performed 4-6 hours later, up to 2 or 3 times a day until the therapy is completed.

EFFECT: method provides the effective treatment of the septic wounds at the various stages by pathogenetically substantiated target in the polymicrobial wound contamination.

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