METHOD OF OBTAINING SUBSTITUTED 1-O-ACYL-2-DEOXY-2-FLUORO-4-THIO-β-D-ARABINOFURANOSES Russian patent published in 2015 - IPC C07D317/18 C07D333/32 C07D333/78

Abstract RU 2559364 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: claimed invention relates to method of obtaining formula I compound and is applicable in pharmaceutical industry. Method includes successive transformation of compounds: IV → V → VI → VII → VIII → IX → X → XI → XII → XIII → I , where R₁ represents -C(O)-C₁-C₆-alkyl or -C(O)-phenyl; R₂ represents C₁-C₆-alkyl, C₁-C₄-perfluoroalkyl or phenyl, R₆ represents C₁-C₆-alkyl or phenylmethylene; R₇ and R₈ represent hydrogen, C₁-C₆-alkyl, C₁-C₄-perfluoroalkyl or phenyl. R₉ represents C₁-C₆-alkyl, C₁-C₄-perfluoroalkyl or phenyl.

EFFECT: claimed is novel method of synthesising compound, promising for obtaining antiviral medications.

30 cl, 1 ex

Similar patents RU2559364C2

Title	Year	Author	Number
COMPOUNDS OF THIENYL[3, 2-d]PYRIMIDINE-4-ON, METHOD FOR PRODUCTION, PHARMACEUTICAL COMPOSITIONS AND THEIR APPLICATION	2012	Lyu Khun Li Tszya Li Tszyan Li Tszingya Van Tszyan Su Minbo Lyan Tsze Tszyan Khualyan Chen Kajsyan	RU2624021C2
AMINOALKYLAMIDOMETHYL-SUBSTITUTED DERIVATIVES OF 2-(4-SULFONYLAMINO)-3-HYDROXY-3,4-DIHYDRO-2H-CHROMAN-6-YL AND MEDICATIONS, CONTAINING SAID COMPOUNDS	2006	Mouloni Brajan Marrison Lester Tsigler Diter Mlinarik Mikhaehl' Bekker Kristiane Veske Mikhaehl' Vitte Klaus Fiser Ivan Brjukkner Rajnkhard	RU2413725C2
2-THIO SUBSTITUTED DERIVATIVES OF IMIDAZOLE AND THEIR USE IN PHARMACEUTICALS	2003	Laufer Shtefan Shtrigel' Khans-Gjunter Toll'Mann Karola Al'Brekht Vol'Fgang	RU2331638C2
METHOD OF PRODUCING COMPLEXES OF RUTHENIUM AND INTERMEDIATE COMPOUNDS THEREOF AND USE THEREOF IN METATHESIS OF OLEFINS	2016	Skowerski, Krzystof Rafal, Gawin	RU2735724C1
DERIVATIVES OF TETRAHYDROISOQUINOLINE, PHARMACEUTICAL COMPOSITION CONTAINING THEREOF, METHOD FOR INHIBITION OF SYNAPTIC UPTAKE OF DOPAMINE AND TREATMENT METHOD	2000	Bek Dzhejms P. Smit Mark A.	RU2293728C2
2-THIO-SUBSTITUTED DERIVATIVES OF IMIDAZOLE, THEIR USING AND PHARMACEUTICAL AGENT BASED ON THEREOF	2002	Laufer Shtefan Kochenrojter Dunja Merkle Filipp Toll'Mann Karola Shtrigel' Khans-Gjunter	RU2284326C2
METHOD FOR PRODUCING SUBSTITUTED 3-PYRIDYLMETHYL AMMONIUM BROMIDES	2009	Joakhim Gebkhardt Frederik Menges Mikhaehl' Rakk Mikhaehl' Kajl' Jokhen Shreder Shtefan Orsten Khel'Mut Tsekh Rodni F Klima Dejvid Kortes Robert Lekht Toni Jegerlener	RU2549896C2
DERIVATIVES OF 2-SUBSTITUTED PHENYL-5,7-DIHYDROCARBYL-3,7-DIHYDROPYRROLO[2,3-d]PYRIMIDIN-4-ONES, THEIR PREPARING AND PHARMACEUTICAL USING	2004	Van Junfehn Chzhao Kehtszjun'	RU2323220C2
ORTHO-SUBSTITUTED ARYLAMIDES, METHOD FOR PEST CONTROLLING, COMPOSITION FOR PEST CONTROLLING, AND INTERMEDIATE	2002	Finkel'Stejn Brjus Lorens Lehm Dzhordzh Filip Selbi Tomas Pol Stivenson Tomas Martin	RU2283839C2
SUBSTITUTED N-(INDOLE-2-CARBONYL)-BETA-ALANYLAMIDES AND THEIR DERIVATIVES, METHOD OF TREATING GLYCOGENPHOSPHORYLAZO-DEPENDENT DISEASES, METHOD FOR PREVENTING ISCHEMIC MYOCARDIUM DAMAGES, AND PHARMACEUTICAL COMPOSITIONS	1996	Bernard Kh'Julin Judit Li Tredvej Vill'Jam Kholt Martin Dennis Dzhej Khuver	RU2159613C2

RU 2 559 364 C2

Authors

Fojgtlander David

Zander Mikhaehl'

Kharre Mikhaehl'

Dates

2015-08-10—Published

2010-12-03—Filed