FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to compounds of formula I or their pharmaceutically acceptable salts. Compounds by invention possess properties of JAK2 kinase inhibitors. In formula I R1 represents phenyl, optionally substituted with 1-3 R6; R2 represents phenyl, optionally substituted with 1-2 R7; R3, R4 and R5 independently represent H. values of the rest of radicals are presented in invention formula. Invention also relates to particular compounds, structural formulae of which are presented in invention formula.
EFFECT: novel compounds, possessing properties of JAK2 kinase inhibitor have been obtained.
11 cl, 2 tbl, 312 ex
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Authors
Dates
2015-08-20—Published
2009-06-19—Filed