FIELD: chemistry.
SUBSTANCE: invention relates to chemical modification of the surface of porous silicon and can be used, in particular, to make a biocompatible and fully biodegradable medical drug carrier, which ensures target delivery thereof and prolonged action in the body. A method of modifying the surface of porous silicon includes two-step treatment of the surface of porous silicon. The first step includes treating the surface of porous silicon with a mixture of bromine and an inert organic solvent at room temperature for 10-30 min, washing the surface of porous silicon with the inert organic solvent and drying until complete removal of the inert organic solvent. The second step includes treating the bromated surface of porous silicon with distilled water, as a result of which the surface bonded bromine is substituted with hydroxyl groups, washing the treated surface of porous silicon with distilled water to remove the formed hydrobromic acid and then drying the treated surface of porous silicon.
EFFECT: invention speeds up biodegradation of porous silicon and enables to preserve the initial pore size and specific surface area.
7 cl, 4 dwg, 3 ex
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Authors
Dates
2015-08-27—Published
2013-12-26—Filed