FIELD: chemistry.
SUBSTANCE: invention relates to chemical modification of the surface of porous silicon and can be used, in particular, to make a biocompatible and fully biodegradable medical drug carrier, which ensures target delivery thereof and prolonged action in the body. A method of modifying the surface of porous silicon includes two-step treatment of the surface of porous silicon. The first step includes treating the surface of porous silicon with a mixture of bromine and an inert organic solvent at room temperature for 10-30 min, washing the surface of porous silicon with the inert organic solvent and drying until complete removal of the inert organic solvent. The second step includes treating the bromated surface of porous silicon with distilled water, as a result of which the surface bonded bromine is substituted with hydroxyl groups, washing the treated surface of porous silicon with distilled water to remove the formed hydrobromic acid and then drying the treated surface of porous silicon.
EFFECT: invention speeds up biodegradation of porous silicon and enables to preserve the initial pore size and specific surface area.
7 cl, 4 dwg, 3 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD FOR PRODUCING BROMINED GRAPHENE BASED ON GRAPHENE OXIDE MODIFICATION | 2022 |
|
RU2806752C1 |
POROUS HYDROPHILIC DIAPHRAGM AND THE METHOD OF ITS PRODUCTION | 2002 |
|
RU2279306C2 |
METHOD OF MODIFYING AT LEAST PART OF POLYMER SURFACE | 1996 |
|
RU2163246C2 |
METHOD OF PRODUCING BROMOBUTYL RUBBER | 2009 |
|
RU2415873C1 |
MICROPOROUS POLYMER MEMBRANE MODIFIED BY WATER-SOLUBLE POLYMER, METHODS OF ITS PRODUCTION AND APPLICATION | 2009 |
|
RU2470700C2 |
OIL EXTRACTION METHODS | 2003 |
|
RU2247235C2 |
OIL EXTRACTION METHOD | 2003 |
|
RU2247231C2 |
POROUS HYDROPHILIC MEMBRANE AND METHOD FOR PRODUCTION THEREOF | 2002 |
|
RU2277436C2 |
METHOD OF PRODUCING MODIFIED DIENE-CONTAINING (CO)POLYMER | 2019 |
|
RU2732776C1 |
METHOD FOR OBTAINING A FUNCTIONALIZED NANOSTRUCTURE BASED ON POROUS SILICON | 2022 |
|
RU2796247C1 |
Authors
Dates
2015-08-27—Published
2013-12-26—Filed