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2 562 539

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IPC

A61K35/74(2015-01-01)

A61K33/14(2006-01-01)

A61K31/685(2006-01-01)

A61P31/02(2006-01-01)

A61P1/00(2006-01-01)

(21) (22)

Application

2014128228/15, 2014-07-09

(24)

Start date

2014-07-09

(22)

Actual filing date

2014-07-09

(45)

Published

2015-09-10

(72)

Inventor

Bakulin Vladimir MikhajlovichMartinson Ekaterina AleksandrovnaTumanov Aleksandr SergeevichLitvinets Sergej Gennad'EvichBakulin Mikhail KonstantinovichBirjukov Vasilij Vasil'Evich

(73)

Holder

Federal'Noe Gosudarstvennoe Bjudzhetnoe Obrazovatel'Noe Uchrezhdenie Vysshego Obrazovanija Gosudarstvennyj Universitet"

METHOD FOR INTESTINAL MICROBIOCOENOSIS CORRECTION Russian patent published in 2015 - IPC A61K35/74 A61K33/14 A61K31/685 A61P31/02 A61P1/00

Abstract RU 2562539 C1

FIELD: medicine.

SUBSTANCE: invention represents a method for intestinal microbiocoenosis correction with the use of the microbial cultures E. coli M-17, B. subtilis "ТПИ" 13, B. licheniformis "ТПИ" 11, B. Bifidum 1, L. plantarum 8P-A3, B. cereus IP5832, B. subtilis 534 characterised by the fact that before use daily doses of the above microbial cultures are supposed to be mixed to perfluordecaline emulsion in normal saline, administered into small laboratory animals in an amount of 0.5 cm³, large domestic, farm and laboratory animals in an amount of 20.0 cm³, and humans in an amount of 10.0 cm³.

EFFECT: 1,2-1,5 times higher antagonist activity of the microbial preparations and 1,2-1,9 higher gastrointestinal survival of the probiotic cultures.

2 ex, 3 tbl

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RU 2 562 539 C1

Authors

Bakulin Vladimir Mikhajlovich

Martinson Ekaterina Aleksandrovna

Tumanov Aleksandr Sergeevich

Litvinets Sergej Gennad'Evich

Bakulin Mikhail Konstantinovich

Birjukov Vasilij Vasil'Evich

Dates

2015-09-10—Published

2014-07-09—Filed