METHOD OF OBTAINING DERIVATIVES OF 7-(HETERO)ARYL-4,5,6,7-TETRAHYDRO[1,2,3]TRIAZOLO[1,5-A]PYRIDINE Russian patent published in 2015 - IPC C07D471/04 

FIELD: chemistry.

SUBSTANCE: invention relates to method of obtaining derivatives of 7-(hetero)aryl-4,5,6,7-tetrahydro[1,2,3]triazolo[1,5-a]pyridine of general formula II where Ar stands for phenyl, possibly containing alkyl or alkoxy-substituents, or pyridyl, substituents R¹ and R² are similar and stand for C(O)OR, where R is alkyl, consisting in the fact that 1-azido-1- [(hetero)aryl]propane of general formula I, where Ar, R¹ and R² have values mentioned above, are subjected to interaction with propargylbromide in toluene medium and dry DMFA in volume ratio 1:1 at room temperature and in presence of NaH suspension in mineral oil, preliminarily prepared at 0°C.

EFFECT: obtaining derivatives of 7-(hetero)aryl-4,5,6,7-tetrahydro[1,2,3]triazolo[1,5-a]pyridine in one stage, without application of catalysts, with high output.

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