PROBIOTIC COMPOSITION FOR APPLICATION IN TREATMENT OF INTESTINAL INFLAMMATION Russian patent published in 2015 - IPC C12N1/20 A61K35/74 A61P1/00 A61P37/02 

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of inventions relates to biotechnology. Claimed are strains of Lactobacillus plantarum CECT 7484, Lactobacillus plantarum CECT 7485 and Pediococcus acidilactici CECT 7483, demonstrating anti-inflammatory activity, immunomodulating activity, activity with respect to IBS or activity with respect to abdominal distension. Also claimed is pharmaceutical composition, containing effective amount of at least one strain, selected from the ones mentioned above, as well as pharmaceutically acceptable excipients. Effective amount of said composition can be used in prevention or treatment of intestinal inflammation, inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), distension and bloating of abdomen in animals, including humans.

EFFECT: group of inventions make it possible to considerably reduce bloating and distension of abdomen, reduce visceral sensitivity, reduce IFNy level, improve life quality of patients with gastrointestinal diseases or conditions.

19 cl, 8 dwg, 10 tbl, 13 ex