USING LEVOFLOXACIN IN AEROSOL FORM FOR TREATING MUCOVISCIDOSIS Russian patent published in 2015 - IPC A61K31/5383 A61K31/4375 A61K31/47 A61K9/12 A61P11/00 

Abstract RU 2563809 C2

FIELD: medicine.

SUBSTANCE: group of inventions refers to medicine and can be used for treating mucoviscidosis in an individual suffering from P. aeruginosa pulmonary infection. That is ensured by administering an aerosol solution containing levofloxacin or ofloxacin in the concentration from approximately 50 mg/ml to approximately 200 mg/ml, and a bivalent or a trivalent cation in the concentration from approximately 50 mM to approximately 400 mM into the individual. That provides reducing expectoration P. aeruginosa density by min. 40%. There are also provided methods of treating mucoviscidosis and a method of reducing small airway resistance.

EFFECT: group of inventions enables reducing bronchial obstruction in the mucoviscidosis patients.

25 cl, 17 dwg, 32 tbl, 5 ex

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RU 2 563 809 C2

Authors

Loutit Jeffery S.

Morgan Elizabeth E.

Dudley Michael N.

Griffith David C.

Lomovskaya Olga

Dates

2015-09-20Published

2010-09-03Filed