FIELD: medicine.
SUBSTANCE: group of inventions refers to medicine, namely to laboratory diagnostics and may be used for measuring total periostin. An anti-periostin antibody contains sequences of hypervariable region ("HVR") SEQ ID NO: 1 and sequences HVR SEQ ID NO: 2 or sequences HVR SEQ ID NO: 3 and sequences HVR SEQ ID NO: 4. The group of inventions also refers to methods for measuring total periostin and a composition for measuring it.
EFFECT: using the presented group of inventions enables identifying high-sensitivity periostin isoforms for diagnosing asthma in a patient.
20 cl, 23 dwg, 8 tbl, 8 ex
| Title | Year | Author | Number |
|---|---|---|---|
| DIAGNOSTICS AND TREATMENT METHODS ASSOCIATED WITH TH2 INHIBITION | 2011 |
|
RU2737245C2 |
| COMPOSITIONS AND METHODS FOR TREATING AND DIAGNOSING ASTHMA | 2009 |
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| USE OF IL-13 ANTAGONISTS FOR THE TREATMENT OF ATOPIC DERMATITIS | 2017 |
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| METHODS OF TREATING OR PREVENTING ASTHMA BY ADMINISTERING IL-4R ANTAGONIST | 2015 |
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| THERAPEUTIC AND DIAGNOSTIC METHODS FOR MAST CELL-MEDIATED INFLAMMATORY DISEASES | 2019 |
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| METHODS FOR TREATMENT OR PREVENTION OF ASTHMA BY ADMINISTRATION OF IL-4R ANTAGONIST | 2018 |
|
RU2793745C2 |
| METHODS FOR INCREASING FORCED EXPIRATORY VOLUME IN ASTHMATIC PATIENTS USING BENRALIZUMAB | 2014 |
|
RU2703568C2 |
| ANTIBODY FORMULATIONS | 2012 |
|
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| METHODS OF TREATING CHRONIC SINUSITIS WITH NASAL POLYPS BY ADMINISTERING IL-4R ANTAGONIST | 2015 |
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| METHODS FOR REDUCING EXACERBATION RATES OF ASTHMA USING OF BENRALIZUMAB | 2014 |
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RU2676333C2 |
