3,5-SUBSTITUTED THIAZOLIDINE-2,4-DIONE DERIVATIVES, HAVING ANTIMICROBIAL ACTIVITY Russian patent published in 2019 - IPC C07D277/20 C07D417/12 C07D277/24 C07D277/34 A61K31/427 A61P31/10 

FIELD: chemistry.

SUBSTANCE: invention relates to a compound of general formula (I) or a pharmaceutically acceptable salt thereof, where R₁ is selected independently and is H, halogen; R₂ is selected independently and is H, halogen; R₃ is selected independently and is H, halogen; X is independently selected and represents OH, halogen, 6-member heterocyclyl containing 2 N atoms, optionally containing a substitute R₄; R₄ is independently selected and represents -C_1-6-alkyl, -C_1-6-alkyl-OH, 4-hydroxy-phenyl, -COCH₃-, -COO-tBu or represents a substitute of following structural formula (a) or (b), wherein the wavy line shows the place of attachment of substitute to fragment X, R₅ is selected independently and is H or phenyl substituted with a halogen atom.

formula (I),

(a),

(b).

EFFECT: compounds of the invention are intended for treating and/or preventing an infectious disease of a microbial aetiology caused by a fungal infection.

13 cl, 11 tbl, 9 ex