METHOD OF TREATING CHRONIC EROSIVE GASTRITIS ASSOCIATED WITH Helicobacter pylori Russian patent published in 2015 - IPC A61B10/00 A61K31/41 A61K31/4412 A61K31/4439 A61K31/02 A61P1/04 

FIELD: medicine.

SUBSTANCE: invention concerns treating chronic erosive gastritis associated with Helicobacter pylori (HP). The oral mucosa HP content is pre-assessed by means of plaque urease test. The oral mucosa HP content is shown by discoloration of Zakse medium. The treatment starts with removing the dental plaque. That is followed by anti-Helicobacter therapy and gingival applications of metronidazole for 30 minutes after tooth brushing after breakfast and at bedtime. If the Zakse medium colour changes from yellow to raspberry red for the first 20 minutes, the high bacterial content is stated. The treatment involves the four-component anti-Helicobacter therapy and the gingival applications for the period of 14 days. If the Zakse medium colour changes in between the 21^st and 40^th minutes, the moderate bacterial content is stated. The treatment involves the 10-day three-component anti-Helicobacter therapy and the gingival applications for the period of 7 days. If the Zakse medium changes its colour by the end of the first hour, the mild bacterial content is detected. The treatment involves the 7-day three-component anti-Helicobacter therapy. During the month following the treatment, the oral cavity is sanitated. The sanitation involves tooth brushing after breakfast and at bedtime for 2 minutes with Mexidol toothpaste with Metrogil Denta gel added in a match head sized amount and mouthwash with 0.05% chlorhexidine bigluconate 15 minutes after tooth brushing. The sanitation is repeated one month before the expected aggravation of the disease.

EFFECT: method enables optimising the treatment of the patients by effective diagnosis and timely prediction of the clinical course of the disease.

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