FIELD: chemistry.
SUBSTANCE: present invention relates to inhibitors of intestinal apical sodium/phosphate co-transport for treating conditions associated with hyperphosphatemia of formula I:
,
pharmaceutically acceptable salts thereof and pharmaceutical compositions based thereon, where R is C2-4alkyl; W is O or S; Z is a single bond or -C(O)-; X1 and X2 are -OH; m equals 1 or 2; and n equals 1 or 2.
EFFECT: novel efficient inhibitors of intestinal apical sodium/phosphate co-transport are disclosed.
32 cl, 6 ex
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