NHE3 BINDING COMPOUNDS AND METHODS FOR PHOSPHATE TRANSPORT INHIBITION Russian patent published in 2022 - IPC A61K31/472 A61P43/00 

Abstract RU 2786149 C2

FIELD: medicine.

SUBSTANCE: inventions group relates to medicine, namely to therapy, and can be used to inhibit phosphate uptake in the gastrointestinal tract. The method for the invention comprises enterally administering to a patient an effective amount of an NHE3 inhibitor. The use of the invention relates to the use of an NHE inhibitor in the manufacture of a medicament for inhibiting phosphate uptake in the gastrointestinal tract.

EFFECT: use of inventions makes it possible to reduce serum phosphorus and serum creatinine, to reduce urinary phosphorus excretion.

31 cl, 14 tbl, 16 dwg, 10 ex

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RU 2 786 149 C2

Authors

Carreras, Christopher

Charmot, Dominique

Jacobs, Jeffrey W.

Labonte, Eric

Lewis, Jason, G.

Dates

2022-12-19Published

2014-04-10Filed