FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to compounds of formula I and their pharmaceutically acceptable salts. In formula I 
R1 is selected from the group, consisting of H; -C1-6-alkyl, non-substituted or substituted with 1 group OH; -(CH2)p-R4, p is equal 0 or 1, R4 represents 6-membered heteroaryl, containing 1 heteroatom of N; -S(O)2-C1-6-alkyl; -C(O)-C1-6-alkyl; and -C(O)O-C1-6-alkyl; R2 is selected from the group, consisting of hydrogen and halogen; R3 represents C6-10-aryl, non-substituted or substituted with 1-2 substituents, individually selected from the group, consisting of halogen, cyano, C1-6-alkyl, C1-6-alkoxy, halogen-C1-6-alkoxy. Invention also relates to pharmaceutical composition, demonstrating antagonism to receptor V1a, containing effective quantity of formula I compound, and to application of formula I compound for manufacturing medication, possessing antagonistic activity with respect to receptor V1a.
EFFECT: novel compounds of formula I, possessing properties of receptor V1a antagonist, have been obtained.
14 cl, 10 tbl, 33 ex
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