FIELD: medicine.
SUBSTANCE: what is presented is a therapeutic agent containing modified pseudovirions of MS2 bacterial virus a coating of which is generated by proteins A and B of MS2 bacterial virus, whereas a portion of genome RNA coding replicase is replace by RNA able to kill cells selectively, which are infected with hepatitis C virus or its RNA replicon; a genome of modified pseudovirions of MS2 bacterial virus is characterised by the nucleotide sequence SEQ ID NO 1.
EFFECT: effective agent for treating chronic VHC infection.
5 dwg, 1 tbl, 13 ex
| Title | Year | Author | Number |
|---|---|---|---|
| CODING DNA (cDNA) FOR MAKING VIRUS-LIKE PARTICLES OF HEPATITIS C VIRUS, METHOD FOR MAKING VIRUS-LIKE PARTICLES AND BASED PHARMACEUTICAL COMPOSITION | 2007 |
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RU2375449C2 |
| METHOD OF TREATING AND PREVENTING HIV INFECTION OF TYPE 1 SUBTYPE A | 2015 |
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| METHOD OF OBTAINING PARTICLES OF BACTERIOPHAGES OF LEVIVIRUS FAMILY | 2020 |
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RU2811106C2 |
| METHOD FOR SELECTIVELY KILLING CELLS | 1999 |
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| PEGYLATED INTERFERON LAMBDA WITH HIGH BIOACCESSABILITY IN ORAL USE AND METHOD FOR PRODUCTION THEREOF | 2017 |
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| METHOD FOR PRODUCING BACTERIOPHAGE HPV AND METHOD FOR PRODUCING MODIFIED BACTERIOPHAGE HPV | 2022 |
|
RU2790451C1 |
| METHOD OF IN VITRO REPRODUCTION OF PROTEOLYTIC ACTIVITY OF HEPATITIS C VIRUS PROTEASE NS3 | 1995 |
|
RU2149185C1 |
| METHOD OF POLY-SIGNAL ACTIVATION OF MALIGNANT SOLID TUMORS CELL APOPTOSIS | 2015 |
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RU2599462C1 |
| ONCOLYTIC TREATMENT METHOD FOR BREAST CANCER | 2018 |
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RU2695136C1 |
| IMMUNOBIOLOGICAL AGENT TO ENHANCE CELLULAR RESPONSE AGAINST HEPATITIS C VIRUS | 2023 |
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RU2811136C1 |
