METHOD FOR SELECTIVELY KILLING CELLS Russian patent published in 2000 - IPC

Abstract RU 2158139 C1

FIELD: medicine. SUBSTANCE: method involves introducing p-cDT plasmida cells containing DNA with nucleotide sequence shown. The sequence encodes pseudo hepatitis C virus "-" RNA and is able to control diphtheria toxin A-subunit synthesis in infected cells. Pseudo hepatitis C virus "-" RNA does not kill healthy cells not infected with hepatitis C virus. Another method version involves introducing pseudo hepatitis C virus "-" RNA into the cells coded with DNA with nucleotide sequence being able to control diphtheria toxin A-subunit synthesis in infected cells. Pseudo hepatitis C virus "-" RNA does not kill healthy cells not infected with. The pseudo hepatitis C virus "-" RNA is produced by means of ПЦР using the DNA with nucleotide sequence shown and carrying out transcription with RNA-polymerase. EFFECT: enhanced selectivity of action upon cells infected with hepatitis C virus. 4 cl, 1 dwg

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RU 2 158 139 C1

Authors

Knjazhev V.A.

Sergienko V.I.

Sivov I.G.

Martynov A.K.

Dates

2000-10-27Published

1999-11-04Filed