ONCOLYTIC TREATMENT METHOD FOR BREAST CANCER Russian patent published in 2019 - IPC A61K35/76 A61K33/24 A61P35/00 

Abstract RU 2695136 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine and molecular biology and can be used for treating breast cancer (BC). Method is carried out by targeted delivery of thallium salts using surface-modified virions of phage MS2, containing cyclic ligand iRGD, having high affinity to integrin avb3 and covalently bonded to the cladding, and a core with genomic RNA with thallium salts.

EFFECT: using the invention enables reducing the tumour size by directing cytotoxic effect on focal and metastatic accumulations of tumour cells.

1 cl, 1 tbl, 2 dwg, 4 ex

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RU 2 695 136 C1

Authors

Bolshakova Tatyana Nikolaevna

Kolesanova Ekaterina Fedorovna

Rybalkina Ekaterina Yurevna

Sivov Igor Gennadevich

Dates

2019-07-22Published

2018-06-19Filed