FIELD: medicine.
SUBSTANCE: invention refers to medicine and molecular biology and can be used for treating breast cancer (BC). Method is carried out by targeted delivery of thallium salts using surface-modified virions of phage MS2, containing cyclic ligand iRGD, having high affinity to integrin avb3 and covalently bonded to the cladding, and a core with genomic RNA with thallium salts.
EFFECT: using the invention enables reducing the tumour size by directing cytotoxic effect on focal and metastatic accumulations of tumour cells.
1 cl, 1 tbl, 2 dwg, 4 ex
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Authors
Dates
2019-07-22—Published
2018-06-19—Filed