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RU

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2 149 185

(13)

C1

(51)

IPC

(21) (22)

Application

96119350/13, 1995-02-14

(24)

Start date

1995-02-14

(22)

Actual filing date

1995-02-14

(45)

Published

2000-05-20

(72)

Inventor

De Franchesko RaffaehleFailla KristinaTomei Lichija

(73)

Holder

Instituto Di Richerke Di Biologia Molekolare P. Andzheletti S.P.A.

METHOD OF IN VITRO REPRODUCTION OF PROTEOLYTIC ACTIVITY OF HEPATITIS C VIRUS PROTEASE NS3 Russian patent published in 2000 - IPC

Abstract RU 2149185 C1

FIELD: biotechnology, virology. SUBSTANCE: reproduction of proteolytic activity of hepatitis C virus protease NS3 is carried out by addition of amino acid sequence NS4A into reactive mixture in combination with protease NS 3 at ratio 1:1. NS3 and NS4A can be added as precursor of NS3 - NS4A. Invention can be used for development of anti-hepatitis C virus protease NS3. EFFECT: increased activity of serine protease NS3 in vitro. 4 cl, 1 dwg, 5 ex

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RU 2 149 185 C1

Authors

De Franchesko Raffaehle

Failla Kristina

Tomei Lichija

Dates

2000-05-20—Published

1995-02-14—Filed

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