FIELD: medicine.
SUBSTANCE: claimed invention relates to field of medicine. Claimed is application of antagonistic anti-NGF antibody in treatment or prevention of urges to urination, associated with interstitial cystitis and/or irritable urinary bladder syndrome, and/or painful bladder syndrome, in subject, where said antagonistic anti-NGF antibody can be represented by E3 antibody or analogous to it antibody.
EFFECT: application of antibody in accordance with invention results in reduction of pain assessment index (NRS) and interstitial cystitis syndrome index (ICSI) expression.
12 cl, 11 tbl, 5 ex
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