FIELD: biotechnology.
SUBSTANCE: this invention relates to biotechnology. Methods for the production of an antibody against the alpha chain of the intreleukin-7 (IL-7Rα) receptor.
EFFECT: resulting antibody can be used in the treatment or prevention of type 2 diabetes and immunological disorders, including type 1 diabetes, disseminated sclerosis, rheumatoid arthritis, graft-versus-host disease and lupus.
12 cl, 15 dwg, 13 ex, 8 tbl
Title | Year | Author | Number |
---|---|---|---|
ANTAGONIST ANTI-IL-7 RECEPTOR ANTIBODIES AND METHODS | 2011 |
|
RU2533809C9 |
ANTIBODIES TO PD-1 AND METHODS OF THEIR APPLICATION | 2015 |
|
RU2701797C2 |
PCSK9 ANTAGONISTS | 2009 |
|
RU2528735C2 |
PCSK9 ANTAGONISTS | 2014 |
|
RU2618869C2 |
METHODS OF TREATING CHRONIC PAIN | 2009 |
|
RU2522493C2 |
METHODS OF OSTEOARTHRITIS PAIN MANAGEMENT BY ADMINISTRATION OF NERVE GROWTH FACTOR ANTAGONIST AND COMPOSITIONS CONTAINING IT | 2006 |
|
RU2429013C2 |
ANTIBODIES SPECIFIC FOR LIGAND 1A, SIMILAR TO TUMOR NECROSIS FACTOR, AND THEIR COMPOSITIONS AND APPLICATION | 2014 |
|
RU2708140C1 |
HUMANISED ANTIBODIES TO Toll-LIKE RECEPTORS 2 AND THEIR APPLICATIONS | 2010 |
|
RU2563344C2 |
ANTIBODIES WITH PH-DEPENDENT ANTIGEN BINDING | 2011 |
|
RU2570729C2 |
TREATMENT OF INTERSTITIAL CYSTITIS | 2008 |
|
RU2570559C2 |
Authors
Dates
2018-05-08—Published
2014-09-05—Filed