PYRAZINO[2,3-d]ISOXAZOLE DERIVATIVE Russian patent published in 2015 - IPC C07D498/04 C07D241/24 C07D261/18 C07C255/29 C07C255/30 C07C237/06 

Abstract RU 2570802 C2

FIELD: chemistry.

SUBSTANCE: invention relates to compounds of formula , where X represents a halogen atom, a hydroxyl group or a sulphamoyloxy group, which is substituted with two alkyl groups containing 1-10 carbon atoms; and Y represents -C(=O)R, where R represents a straight, branched or cyclic alkoxy group containing 1-10 carbon atoms, which can be substituted with an aryl group containing 6-10 carbon atoms; a pyrrolidino group or an amino group, which can be substituted with one or two alkyl groups containing 1-10 carbon atoms, which can be substituted with an aryl group containing 6-10 carbon atoms. The invention also relates to methods of obtaining special cases of compounds of formula (I), methods of producing compounds of formulae

and

from compounds of formula (I), to intermediate compounds of formulae

, and for producing compounds of formula (I).

EFFECT: derivatives as intermediate compounds for producing 6-fluoro-3-hydroxy-2-pyrazine carboxamide, which is suitable for treating and preventing influenza virus.

15 cl, 54 ex

Similar patents RU2570802C2

Title Year Author Number
METHOD OF PRODUCING THIOPHENE DERIVATIVE AND INTERMEDIATE PRODUCT THEREOF 2009
  • Janagikhara Kazufumi
  • Umezava Singo
  • Mijadzi Katsuaki
RU2495877C2
HETEROCYCLIC COMPOUNDS APPLICABLE AS ALLOSTERIC EFFECTORS IN MUSCARINE RECEPTORS 1995
  • Bedsehll Najdzhel
  • Lazareno Sebast'Jan
  • Naruto Siundzhi
  • Masakhiko Sugimoto
  • Kojama Kazuo
  • Marumoto Sindzhi
RU2152385C1
DERIVATIVE CYCLIC AMINE AND ITS PHARMACEUTICAL APPLICATION 2014
  • Morita Yasukhiro
  • Izumimoto Naoki
  • Iseki Katsukhiko
  • Ivano Sunsuke
  • Udagava Sudzi
  • Mijosi Tomoya
  • Osada Yudzi
  • Koreeda Tetsuro
  • Murakami Masanori
  • Siraki Motokhiro
  • Takakhasi Kej
  • Josida Kejyu
RU2638549C2
CONDENSED SUBSTITUTED AMINOPYRROLIDINE DERIVATIVE 2007
  • Takakhasi Khisasi
  • Komorija Satosi
  • Kitamura Takakhiro
  • Odagiri Takasi
  • Inagaki Khiroaki
  • Tsuda Tosifumi
  • Nakajama Kijosi
  • Takemura Makoto
  • Josida Keniti
  • Mijauti Rie
  • Nagamoti Masatosi
RU2443698C2
PYRIMIDINE NUCLEOSIDE DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS AND METHOD OF THEIR SYNTHESIS 1992
  • Masakatsu Kaneko[Jp]
  • Khitosi Khotoda[Jp]
  • Tomojjuki Sibata[Jp]
  • Tomovo Kobajjasi[Jp]
  • Esikhiro Mitsukhasi[Jp]
  • Akira Matsuda[Jp]
  • Takuma Sasaki[Jp]
RU2085557C1
METHOD OF PRODUCING ALKYL-SUBSTITUTED 2-DESOXY-2-FLUORO-D-RIBOFURANOSYL-PYRIMIDINES AND PURINES AND DERIVATIVES THEREOF 2005
  • Vang Pejjuan
  • Stets Vojtsekh
  • Chan Biung-Kvon
  • Shi Dzhanksing
  • Da Dzhinfa
RU2407747C2
METHODS FOR PREPARING GLUTAMIC ACID DERIVATIVES, METHODS FOR PREPARING INTERMEDIATES, AND A NOVEL INTERMEDIATE FOR GIVEN METHODS 2002
  • Kavakhara Sigeru
  • Amino Jusuke
  • Mori Keniti
  • Funakosi Nao
  • Takemoto Tadasi
RU2305677C2
1-THIO-D-GLUCITOL DERIVATIVES 2006
  • Kakinuma Khirojuki
  • Khasimoto Juko
  • Oi Takakhiro
  • Takakhasi Khitomi
RU2387649C2
TAXANE SYNTHESIS INTERMEDIATES AND METHODS OF PREPARATION THEREOF 1996
  • Ljuk Shantelu
  • Brjuno Shovo
  • Kristin Korbehn
  • Rober Dal'
  • Sonija Le Gen
  • Arno Lami
  • Antuan Leze
  • Zhan-P'Er Robehn
RU2159237C2
SPIROKETAL DERIVATIVES AND USE THEREOF AS MEDICINAL AGENT AGAINST DIABETES 2006
  • Kobajasi Takamitsu
  • Sato Tsutomu
  • Nisimoto Masakhiro
RU2416617C2

RU 2 570 802 C2

Authors

Nakamura Kouki

Murakami Takesi

Naitou Khirojuki

Khanaki Naojuki

Vatanabe Katsujuki

Dates

2015-12-10Published

2011-11-11Filed