FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to biochemistry. Described is acylated, stabilised with respect to proteases insulin. Application of the described insulin for the production of a pharmaceutical composition for the treatment or prevention of hyperglycaemia, type 2 diabetes mellitus, impaired tolerance to glucose and type 1 diabetes mellitus is presented.
EFFECT: invention makes it possible to obtain the insulin analogues, stable to proteases.
24 cl, 11 dwg, 1 tbl, 184 ex
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Authors
Dates
2015-12-20—Published
2009-03-13—Filed