FIELD: medicine.
SUBSTANCE: invention relates to compound of structural formula (1), which possesses inhibiting activity with respect to rotamase «FKBP12». In formula 
R1 represents formulae 
or 
X represents -(CH2)m-X1-(CH2)n-; X1 represents bond, -O-, -NRaC(=O)-, -C(=O)NRb-, -NRcS(=O)2- or -S(=O)2NRd-; Ra, Rb, Rc and Rd, each can be similar or different and represent hydrogen atom or C1-6alkyl group; m and n, each, can be similar or different and represent integer number 0-3; R2 represents phenyl group, pyridyl group, pyridazyl group, pyrimidyl group or pyrazinyl group. Values of ring A radical and substituents of R2 radical are disclosed in invention formula. Invention also relates to pharmaceutical preparation, which contains claimed compound, and to medication for prevention of treatment of alopecia.
EFFECT: increase of treatment efficiency.
12 cl, 3 dwg, 1 tbl, 24 ex
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