EASILY DOSED SOLID MEDICINAL PREPARATION Russian patent published in 2016 - IPC A61K9/30 A61K47/32 A61K47/02 A61K47/26 A61K47/38 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to chemical-pharmaceutical industry and represents a composition for coating an orally administered medicinal preparation, containing: a first thickening agent specified in a group consisting of carboxyvinyl polymer and sodium alginate; a polyvalent metal compound representing a pharmaceutically acceptable salt of polyvalent metal, e.g. calcium, magnesium, aluminium and zinc; at least one type of a second thickening agent specified in a group consisting of xanthum gum, guar gum and sodium alginate; provided the first thickening agent is sodium alginate, the second thickening agent is other than sodium alginate; the composition also containing hydroxypropylmethyl cellulose and sugar or sugar alcohol having a solubility of 30 g or more in 100 g of water at 20°C.

EFFECT: invention provides producing a coating masking the off-flavour of a medicinal preparation, ensuring better solubility and facilitates tablet swallowing (a tablet easily slides over a mucous membrane).

22 cl, 12 ex, 5 tbl