FIELD: medicine.
SUBSTANCE: claimed composition contains pharmaceutical agent, carrier for retarded releasing of drug and accelerator of gel hydration. Carrier represents mixture of sodium alginate and xanthan gum in weight ratio of 1:0.1-10. Accelerator of gel hydration represents mixture of hydroxypropylmethyl cellulose and propylene glycol alginate in weight ratio of 1:0.05-20. Weight ratio of pharmaceutical agent, abovementioned carrier and abovementioned accelerator of gel hydration is 1:3-45:1-0.1-15. Said composition is capable of supporting stable levels of pharmaceutical agent in blood for 24 hours or more.
EFFECT: effective composition of retarded releasing for peroral drug administration.
5 cl, 8 dwg, 3 tbl, 21 ex
Authors
Dates
2007-03-20—Published
2003-10-23—Filed