FIELD: medicine, pharmaceutics.
SUBSTANCE: in formula (I) R represents (C1-C7)alkyl or (C2-C7)alkenyl, wherein R is substituted by one or more substitutes optionally specified in R1; wherein R1 represents cyano or (C1-C4)alkyl, (C6)cycloalkyl or (C6)aryl each of which may be optionally substituted by one or more substitutes optionally specified in R2, wherein R2 represents (C1-C4)alkyl or -COORc or =N-ORa, -NRaRb or =O; Ra and Rb independently represent (C1-C4)alkyl or (C6)aryl; Rc represents (C1-C4)alkyl. The invention also refers to a pharmaceutical composition containing the above compound.
EFFECT: invention refers to the compound of structural formula I, which can be used to prevent, treat or reduce an intensity of symptoms of a disease or condition susceptible to IL-8 keratinocyte release stimulation, susceptible to neutrophil oxidative burst stimulation or susceptible to necrosis induction.
24 cl, 121 ex
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Authors
Dates
2016-02-20—Published
2011-12-22—Filed