FIELD: bioengineering.
SUBSTANCE: compounds or structures are suggested, in particular proteins and polypeptides that include or, in essence comprise one or three such amino acid sequences. Also the invention relates to the nucleic acids encoding the said amino acid sequences and polypeptides, to pharmaceutical compositions, to methods of medical treatment and preventive treatment relating to hRSV infection.
EFFECT: polypeptides and compositions under the invention show the improved stability, lower immunogenicity or improved affinity and/or avidity in relation to F hRSV protein.
28 cl, 21 dwg, 16 tbl, 22 ex
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