FIELD: medicine.
SUBSTANCE: invention relates to medicine and consists in liposomal composition for delayed release of medication, including first liposome, which contains external membrane, consisting of multilayered lipid bilayer; and multitude of second liposomes, located in internal area of first liposome, determined by external membrane of first liposome, where each of second liposomes has external membrane, consisting of multilayered lipid bilayer, where liposomal composition has internal areas of second liposomes, each of which is determined by external membrane of each of second liposomes, with ionic gradient formed at least between each of internal areas of second liposomes and external medium of first liposome. Invention also deals with method of obtaining liposomal composition.
EFFECT: delayed release of medication, which can suppress pain, persisting for 5-7 days after operation.
8 cl, 5 dwg, 7 tbl, 15 ex
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Authors
Dates
2016-03-20—Published
2011-12-27—Filed