METHOD FOR RAPID DIAGNOSIS OF RESISTANCE AND SUSCEPTIBILITY TO ACETYLSALICYLIC ACID Russian patent published in 2016 - IPC G01N21/21 G01N33/49 

FIELD: medicine.

SUBSTANCE: invention can be used for rapid diagnosis of resistance and sensitivity to acetylsalicylic acid (ASA). For this blood sampling is performed in the patient prior antiplatelet therapy. As used anticoagulant 3.2% sodium citrate, 0.5 ml of blood was placed into test cuvette, the blood sample is passed through a short, of the order of 10^-5 with a current pulse with registration function decline polarization of the sample, and then perform the Fourier transform of this function and parameters are calculated impedance locus in the frequency range 0.1-125 kHz using a dielectric Fourier spectrometer. For values of the reference interval r0=4.518-4.551, x0=1.925-1.939, y0=-1.395--1.385 diagnose sensitivity, while values of r0=4.504-4.517, x0=1.914-1.926, y0=-1.384--1.375 - resistance to acetylsalicylic acid.

EFFECT: invention makes it possible to quickly and reliably carry out the diagnosis of resistance to ASA in a patient prior to treatment that will prevent the development of unwanted coronary events in patients with coronary artery disease.

1 cl, 2 dwg, 2 tbl, 2 ex