QUINOLYL PYRROLE PYRIMIDYL CONDENSED COMPOUND OR SALT THEREOF Russian patent published in 2016 - IPC C07D471/14 A61K31/519 A61P35/00 

Abstract RU 2581039 C1

FIELD: chemistry.

SUBSTANCE: present invention relates to new compound of formula (I) or its pharmaceutically acceptable salt, which have inhibitory effect on EGFR and acts as cell growth inhibitor. In formula: m equals 1 or 2; n equals 1 or 2; group R1 is hydrogen atom or C1-C4-alkyl group; and R2, R3 and R4 can be identical or different, and each of them represents hydrogen atom, halogen atom or group presented by formula (a)-CH2-N(R5)(R6)(a), wherein R5 and R6 can be identical or different and each of them represents C1-C4-alkyl group.

EFFECT: compounds can be used for preparing pharmaceutical composition effective for preventing and/or treating cancer, based on inhibiting effect of compound with respect to EGFR.

10 cl, 2 tbl, 25 ex

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RU 2 581 039 C1

Authors

Sagara Takesi

Ito Satoru

Otsuki Satie

Nonosita Katsumasa

Dates

2016-04-10Published

2013-02-22Filed