TRANSDERMAL AGENT FOR TREATING AND PREVENTING JOINT AND SOFT TISSUE DISEASES, METHOD FOR PRODUCTION THEREOF AND COMBINED TRANSDERMAL PREPARATION FOR TREATING AND PREVENTING JOINT AND SOFT TISSUE DISEASES Russian patent published in 2016 - IPC A61K31/13 A61K31/351 A61K31/192 A61K9/107 A61P19/02 

Abstract RU 2582278 C2

FIELD: medicine.

SUBSTANCE: invention relates to medicine and provides transdermal agent for treating and preventing joint and soft tissue diseases. Agent contains glucosamine cartilage protector; non-steroid anti-inflammatory drug ketoprofen; pharmaceutically acceptable base containing a mixture of solvent N-methylpyrrolidone and propylene glycol; antioxidant for cartilage protector, specifically lidocaine and citric acid; gelling agent, capable of forming gels in an acidic medium, and an emulsifier in form of a nonionic surfactant. Acidity varies from pH 2.9 to 2.2. Invention also relates to a method of producing a transdermal agent.

EFFECT: technical result consists is a wider range of products, high stability, high degree of transdermal penetration of active component and minimal side effects.

12 cl, 1 dwg, 6 tbl

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RU 2 582 278 C2

Authors

Ljapunov Nikolaj Aleksandrovich

Ljapunov Aleksej Nikolaevich

Bezuglaja Elena Petrovna

Sheludchenko Olga Sergeevna

Jakunina Julija Sergeevna

Dates

2016-04-20Published

2013-04-25Filed